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This result is in accordance with the fast upregulation of TIRC7 at the cell membrane upon lymphocyte activation and the clustering of the molecule at the cell – cell adhesion site [16] where the immunological synapse is formed [15].
We also show that a non-scanning surface plasmon microscope combined with the scanning localized surface plasmon microscope contributes to observing an entire cell adhesion site and identify regions of interest.
The MDP used to create hydrogels has the sequence K SL 3RG SL 3KGRGDS, containing a matrix metalloproteinase 2 (MMP2) sensitive cleavage site LRG and a cell adhesion site RGD.
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These materials are biocompatible, biodegradable and contain cell adhesion sites.
Using cell adhesion sites, cells alter their adhesion and cytoskeleton in response to these extracellular cues.
The line width, node size and gap size in-between cell adhesion sites was varied systematically.
Human hair proteins (KER) are biocompatible, biodegradable, and possess abundant cell adhesion sites.
PEG albumin hydrogels exhibited poor cell spreading and migration by virtue of the fact that the albumin backbone lacks any known cell adhesion sites.
Cell migration and transfection were simultaneously measured within hydrogels with varying density of cell adhesion sites (Arg-Gly-Asp peptides) and solids content.
This study employs the blending of desired characteristics of a synthetic polymer, poly (l-lactic acid) (PLLA) and a biopolymer, gelatin for enhancing cell adhesion sites.
This function relies not only on intrinsic material properties but is also determined by dynamic interactions with other cytoskeletal filament systems, distinct cell adhesion sites, and cellular organelles which are fine-tuned by multiple signaling pathways.
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