Sentence examples for cell addicted from inspiring English sources

In 1988 I woke up in a padded cell, addicted to drugs, committed to a life of crime and violence, and wanting to die.

This metabolic behaviour, now known as the Warburg effect, renders most cancer cells addicted to glucose.

Constitutively activated prosurvival pathways render cancer cells addicted to their effects.

Cancer cells addicted to an oncogenic pathway often have multiple built-in escape routes leading to drug resistance.

Thus, the impact of PEPD on ErbB2 is predominantly inhibitory, and PEPD targets cells addicted to ErbB2.

We observed that myostatin induced significant mitochondrial metabolic alterations and prolonged exposure of myostatin induced mitochondria-dependent apoptosis in cancer cells addicted to glycolysis.

Upon direct knockdown of miR-21 in tumor cells, addicted to miR-21 expression, apoptosis is induced [ 9] and Figure 7 in this paper.

Importantly, a subset of these breast cancers are driven by a Notch fusion gene, which renders the cells addicted to the Notch pathway for survival.

Nevertheless, the inhibition of cyclin D1 and proliferation by MTA might have a more pronounced effect in cells addicted to oncogenes with potent mitogenic effects.

These findings may also aid in understanding why cells addicted to glucose are more sensitive to myostatin, and serve to explain why certain malignant tumor cells are more sensitive to myostatin than cells in normal tissue.

Furthermore, DTPs are detectable in many cancer cell lines following treatment with multiple cytotoxic and targeted agents, whereas induction of SOX2 appears to be strictly limited to targeted EGFR inhibition in cells addicted to mutant EGFR signaling.