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Hayflick et al described an individual cell's capability to multiply as doubling potential [13].
Conjugation of DA-quinone with glutathione limits the cell's capability to deal with oxidative stress.
This would promote the cell's capability to respond and adapt to environmental changes and explore new environmental niches.
We, therefore, considered that α-enolase has the potential to reinforce the cell's capability for DNA repair, as it was upregulated only in the CDDP-specific resistant cells.
Therefore, strategies aiming at re-establishing the cell's capability to activate a cell death program are an area of active research.
Radiation-induced persistently increased ROS and DNA damage could lead to sustained cell-cycle arrest potentially leading to senescence [ 89] and the cell's capability to repair DNA damage including DSB have been reported to decline with advancing age [ 17, 19- 21].
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He says it will take years to fully exploit Cell's capabilities.
There are obvious links between cell's capabilities to sense changes in extracellular environmental conditions with concomitant large-scale adaptation of genome expression.
However, in situations where ROS production exceeds the cell's antioxidant capability, cell death can occur by interfering with normal physiological processes and the modification of cellular biomolecules [28].
In this way, polySia can facilitate cell migration and plasticity as well as increase the cell's invasion capability [ 8].
Depletion of β1- and β3-integrins in A-172 and U-138 cells strongly supported these findings and almost completely abrogated the cell's adhesive capability.
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