Microarrays were normalized using the MAS5 algorithm, and expression threshold and ceiling values were applied as described [8].
The GCT file was then used in the PreprocessDataSet module, where threshold and ceiling values were set (floor 20 ceiling 20,000, fold = 1.5, delta = 1), and any value lower/higher than the threshold/ceiling were reset to the threshold/ceiling value, and data were processed to discard any invariant genes.
The distance between the MSE expressions is small at low SNR, increasing with SNR until a ceiling value is reached.
The "ceiling value" was the best possible value of the item or the maximum total value of the scale.
The floor value is considered to be the percentage of patients who have the lowest value and the ceiling value is the percentage of patients with the highest value.
For example, when the ceiling value is 700,000 XOF (equivalent to $1600) for example, the coefficients obtained from the OLS regression for the overall sample, populations in Nouna town, and populations in Nouna villages are 37664 XOF, 77075 XOF, and 20354 XOF respectively.
Preliminary results with tests detecting only S100B-S100B dimers have demonstrated, as expected, that the ceiling for "normal values" is significantly lower than the published "0.1 ng/ml" dogma [1], [6], [10], [14], [19], [24], [40], [44] [46].
With the exception of item K35 (0.81) and item K33 (0.84) which tended to have a ceiling effect, all values were in the acceptable range from 0.2 to 0.8.
Additionally for the radiant wall-ceiling integrated cases, HTC values were obtained for the wall and ceiling panels separately.
For subtests in which a ceiling was not achieved (< 10%), missing values were imputed based on scores obtained by other children with similar score patterns.
