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At 1.0 and 2.5 μM proliferation of the cells is slowed initially with the cells eventually ceasing proliferation after 30 days.
Finite cell line: a cell line that survives for a fixed number of population doublings, usually ∼40 60, before senescing and ceasing proliferation.
We therefore conclude that TIFs are passed from mitosis into the G1 cell cycle phase, and that normal human cells tolerate a small number of DDR+ telomeres without ceasing proliferation.
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Furthermore, the cells expressing Bcl-xLΔ continued to proliferate following infection while CHO-bcl-xL ceased prolimmediatelymmediately following infection.
EP156T cells grow in a monolayer and cease proliferation upon reaching confluence, a phenomenon referred to as cell contact inhibition.
In late passages of MEFs, when the cells had ceased proliferation and adopted a senescence like phenotype, nestin positive cells were hardly detectable.
During mid-oogenesis the epithelial FC cease proliferation (stage 7), and form a cuboidal epithelium surrounding the whole egg chamber (stage 8) [37].
The BJtsLT cells grown at 39°C cease proliferation unless a shRNA is expressed that inactivates the p53-dependent anti-proliferative response.
Upon transfer to 37°C and withdrawal of interferon, SV40 expression is turned off and existing T antigen is inactivated whereupon the cells cease proliferation and differentiate over 6 14 days [29].
As discussed above, a critical feature of bona fide neural stem cells is their ability to cease proliferation – except for some residual mitotic activity related to astroglial cells and late neural progenitors – and to have their progeny undergoing terminal differentiation upon growth factor removal and plating onto an adhesion substrate [25].
The journey is meant to cease proliferation and start neuronal differentiation.
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