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Third, expertise with Zamboni's procedure, but not general CDS expertise, improved the ability to detect CCSVI.
Zamboni-trained sonographers ascertained CCSVI more frequently than non-trained sonographers, whereas general CDS expertise and the tertile period of the study had no effect (table 4).
As to the general CDS expertise, the κ value was 0.16 (−0.20 to 0.52) for high experts (29 comparisons), and 0.26 (−0.04 to 0.55) for comparisons between one high expert and one low expert (N=42); no calculation was possible for the non-expert (N=13) since one of the two operators did not find any positive patients.
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But expertise is fungible.
Announced last July, the merger had envisioned a new public company that would have capitalized on CDNow's Internet expertise and on Columbia House's broad reach and experience in selling low-cost music by direct mail.
"We were looking for something very specific," someone with motion-capture expertise, says CDI's Director Carol Strohecker, "but we cast the net very broadly".
To increase the study's trustworthiness the researchers were from varying disciplines and contributed with expertise in CD research, pediatric medicine, qualitative research, and nursing.
This is especially valuable when comparing wild-type and mutant proteins, as in Figure 5 figure supplement 1, where CD deconvolution can assist readers with less expertise in interpreting the raw CD data.
A reported CD diagnosis based on medical expertise was required for inclusion.
CD and DJ provided technical expertise for the analysis and interpretation of the data and were involved with the manuscript development.
Brief intervention expertise was provided by CD, EK, NH and JS.
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