However, the substitution of H52BQ, H52CS, H54N, H61E, L31F, L55S, L90W, L92D, L93Y and L96R in CDR regions may potentially alter the CDR's conformation, and V59, an additional non-conserved surface residue in light chain near the CDR2 within 5 Å, may potentially affect the binding affinity too.
But Acyl died on 19 July, replaced by Acheikh ibn Oumar, and the CDR was antagonized by Habré's eagerness to unify the country, which led him to overrun the CDR's domains.
Federal investigators in New Mexico had previously looked at CDR's involvement in bond sales in that state, as well as its contributions to Gov. Bill Richardson.
Prosecutors said that CDR's company's owner and president, David Rubin, vice president Evan Zarefksy and former chief financial officer Zevi Wolmark took part in two wire fraud schemes.
Replacing those struck with Lehman, as spreads widened after its bankruptcy filing, is thought to have cost some dealers upwards of $200m each.That risk remains, judging by CDR's counterparty-risk index, which measures the health of CDS dealers (see chart 1).
In 2003 and 2004, CDR's president, David Rubin, a major Democratic contributor, gave about $100,000 to two political action committees controlled by Mr. Richardson, as well as $10,000 to his re-election campaign in 2005, according to published reports.
