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However, stratification by severity of disease, as defined by the presence of endoscopic lesions (CD) and Mayo sub-endoscopic criteria (UC), shows that MEFV expression is upregulated in both severely affected CD (fold change = 12.58±5.11; p<0.001) (Figure 1C) and UC (fold change = 6.23±1.97; p<0.008) (Figure 1D) patients compared to healthy controls.
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The cytochrome c fold presents five α-helices and a short antiparallel β-strand on one face and two extended loops on the other (Fig. 3) [24], [25], [25], [2].
c Fold change as determined from the microarray data.
c Fold increase (FI) or fold decrease (FD) in MIC and in the presence of Dcl.
General features of the class I cyt c fold are shown in Figure 5.
c Fold change of gene expression in uterine fibroids vs myometrium.
(c) Fold change (log2) increase in testis expression vs carcass expression is shown for two testis-specific miRNAs.
F C: Fold change in mRNA expression of CPE of AD (Braak 5,6) vs. healthy (Braak 0,1) donors.
The gene datasets that were generated were ipsilateral vs naïve (TBI-I) and contralateral vs naïve (TBI-C) fold changes.
The class I cyt c fold is recognized as having a total of five α-helices arranged in a unique tertiary structure.
Furthermore, Alba's IF3-C fold is found in many other families lacking sequence similarity but recognizable at the structural level.
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