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Overall, HFD-fed mothers had a weight gain that was higher than CD fed mothers (14.0±0.3g vs 10.3±0.3g, p = 0.0001), but when the weight gain is reported in relation to the number of fœtuses, there was no difference in weight gain between animals on the two different diets (2.0±0.13g vs 1.8±0.13g, p = 0.2173).
Strikingly, there was no dispersion in CD fed mice and dispersion was significantly reduced in KD fed animals (Fig. 5E,F; F3,15 = 5.26, p < 0.05 for both treatments).
CD fed mice, as KD mice, did not show spontaneous seizures or early signs of abnormal activity without KA injection (n = 4 for both diets; Supplementary Figure 1).
As well, CD fed mice are much less susceptible to PTZ induced seizures and are largely protected against chronic seizures as well as cytological and molecular changes in the KA model of epilepsy.
In contrast, CD fed mice blood (n = 6) showed high glucose and pyruvate levels, and very low levels of βHB and ACA, similar to SD controls (all p > 0.05).
(A,C) Corroborating this finding, the frequency of interictal events (example shown by an arrow) was found to be significantly reduced in both KD and CD fed mice compared to SD controls (all p < 0.05).
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The fully-sealed CNTs FED (c-FED) showed good emission properties.
The dead sperm percentage decreased (P < 0.05) in vitamin C fed group, whereas, sperm concentration did not differ (P > 0.05) between the control and treated groups.
Overnight fasting blood glucose differs significantly between H fed rats and C fed rats.
Liver and kidneys from H fed rats had higher wet weights as compared to C fed rats as observed in previous study [ 17] while no changes in wet weight of spleen and hearts.
The developed technology has a potential practical application in c-FED.
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