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Health effects included in the CUA were CC, time to CC, safety in terms of LSR risks and durations, recurrences, and QoL.
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Secondary endpoints included: CC-930 pharmacokinetics; evaluation of the long-term safety of CC-930 in the 52-week open-label extension; and disease progression and death rates within the total treatment and follow-up observational period.
Prospective, observational study comparing two periods through rounds of audits in which data related to the use of Alaris® CC syringe infusion pump safety systems was collected in a level III-C NICU with around 500 admissions per year in intensive care.
Previous studies that explored different combination regimens involving capecitabine prompted us to design this randomized phase II trial in order to evaluate the efficacy and safety of CC and CP regimens in patients with metastatic esophageal squamous cell carcinoma who had not been previously treated.
The primary objective was to evaluate the pharmacokinetics, pharmacodynamics, biologic activity, and safety of CC-930.
The second study was designed to evaluate the safety, pharmacokinetics, and pharmacodynamics of CC-930 in IPF patients.
Currently, clinical trials are underway with BEZ235 and CC-115 to determine its efficacy and safety in human patients [ 66].
Occupational health and safety issues were paramount for the CCs in the field.
First, the safety risk in a different, high-risk patient subgroup of CC patients was predicted.
ISSUE: The Warren G Magnuson Clinical Center (CC) strives to achieve a balance between its mission and worker and patient safety.
Safety first Image: Lars Plougmann, Our big boy enjoying the drive through Mexico City via Flickr CC BY 2.0.
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