In this paper, we have investigated the full range of CBP bound regions to determine if CBP is involved in any additional processes that have yet to be identified.
As a result, differences observed between the methods could be due primarily to the low range of CBP levels and may not reflect the real impact of the method applied to the subject's exposure assessment.
Cellulolytic clostridia such as Clostridium thermocellum and C. stercorarium are among the most widely studied organisms for CBP, producing a wide range of cellulases, xylanases and other lignocellulolytic enzymes [ 3].
In order to establish relationships between the E. siliculosus sequences and other LHC proteins identified in chlorophyll a/b-, chlorophyll a-, and chlorophyll a/c-containing organisms, phylogenetic analyses with CBPs from a wide range of taxa were performed.
CBP is subjected to a range of post-translational modifications including acetylation [3], phosphorylation [4 7], ubiquitylation [8,9] and SUMOylation [10] which regulate its functional interactions, activity and stability.
Since the TTHM and exposure categories were based on levels measured in the entire area, the differences in the range of measured CBP levels between systems could bring about a bias on the observed impact of the assignment method.
Moreover, the histone acetyl transferase CBP, previously implicated in long-range β-globin activation [35] remains associated with the β-globin LCR and promoter (Figure 5A).
In Section 5, it will be shown that by applying our CAC scheme, the amount of improvement in CBP is considerable for a vast range of hand-off rates which motivates its application in 4G vehicular networks.
Cellulolytic clostridia are among the leading CBP candidates due to their wide carbon substrate range that include cellulose.
Taken together, our results show that CBP is bound at genomic sites with a wide range of functions.
