Sentence examples for causing transformation from inspiring English sources

The cascade of these effects can lead to further deterioration of adaptation, causing transformation or chronification of the disease [33].

Thus, it may be speculated that NEU may play a role in causing transformation in breast acini grown as 3D cultures.

We therefore hypothesise that the progenitor cells within this population are more epigenetically unstable, regardless of their association with potentially epigenome-modifying genetic mutations, which results in hypermethylation of tumour suppressor genes, giving selective advantage and causing transformation.

FGF8 is able to function as an oncogene, causing transformation of NIH3T3 cells and inducing breast tumours in transgenic mice expressing FGF8 under an MMTV promoter (Kouhara et al, 1994; Daphna-Iken et al, 1998).

From the Oligocene ca. 30 Ma to middle-to-late Miocene, shrinkage of the Paratethys played an important role in causing transformation of the Central Asian climate from an oceanic to a continental condition [ 55].

Finally, breast epithelial cells were grown as 3-dimensional spheroid cultures to study whether NEU can induce upregulation of vimentin as well as disrupt cell polarity of the breast acini, thus causing transformation of epithelial cells in culture.

Major advances in the understanding of growth control have come from studies of the viral genes that cause transformation.

Joule heating of Mo6S3I6 nanowires also causes transformation into Mo NW via thermal decomposition.

Many of these have phytochemical or pharmacological properties [34], and may be able to cause transformation of episodic headache to pMOH.

His experience causes transformation and he returns to his original world with a treasure benefit this world.

Further, inhibition of PKR and subsequent reduced phosphorylation of eIF2α was sufficient to cause transformation of mouse NIH3T3 fibroblasts [22].