Sentence examples for causing the expression of from inspiring English sources

Activation of MC1R leads to an increase in cAMP levels, causing the expression of the transcription factor MITF. MITF regulates the expression of the enzymes involved in melanogenesis as well as genes important for the survival and proliferation of melanocytes.

(a) The first network illustrates the up regulation of TGFBRII facilitating oxidative stress and causing the expression of early transcription genes via MAPK pathway leading to cardiovascular and kidney related complications.

The presence of high GST activity in control-fed snails could indicate that some lipophilic gorgonian compounds and/or their metabolites may persist in snail tissues even after feeding has ceased, causing the expression of GSTs to be maintained.

In gCJD, mutations in the PRNP gene predispose to disease [ 7, 8] by causing the expression of PrP protein with modified primary structure.

They hypothesized that E178G is a hypomorphic mutation, causing the expression of a protein that still retains some residual activity, leading to a milder phenotype.

The high levels of AFP in this patient originally raised the question as to whether there was a tumor or another condition causing the expression of AFP.

The smoke fume, principal factor in the development of lung cancer, causes the expression of certain cytokines, including interleukin 4, 6, 8 and 10, which may act by inhibiting apoptosis and interfere cellular repair mechanisms and angiogenesis.

This bacterium has also been shown to activate lung T cells [20] and cause the expression of reactive oxygen species and proteases in patients with COPD [21].

The binding of PhaR to DNA and to am-P 3HB) am-P 3HBimilar k on valueshowedgesimilarhat a concentration-dependent effect caused the expression of phaP with dissociation of PhaR from the phaP promoter region.

Upon stimulation, IκBα is degraded and free NF-κB subunits to enter the nucleus and subsequently cause the expression of inflammatory genes which are the main regulatory enzymes for NO [9].

Unfortunately, when chronic inflammation remains for long periods of time and is not addressed adequately, it will cause the expression of genes that lead to degenerative conditions such as coronary artery disease, arthritis, cancer and others.