Sentence examples for causing the activation of from inspiring English sources

This indicates a compromised selectivity for Na+ and (consistent with observations of Favre et al. [18]) an increase in Ca2+ permeability possibly causing the activation of Ca2+-activated Cl- currents.

CRP activates FcγRs, which phosphorylate immunoreceptor tyrosine-based activating motifs, causing the activation of Syk (spleen tyrosine kinase) and in turn initiating downstream signaling cascades [ 29].

Epidermal growth factor receptor (EGFR) is often hyper-activated in many lung cancers due to the presence of a mutation in the kinase domain, causing the activation of multiple cell survival signals, especially Akt and mitogen-activated protein kinase (MAPK) pathways.

Numerous studies have shown that fever enhances the immune response by increasing mobility and activity of white cells, stimulating the production of interferon, causing the activation of T-lymphocytes, and indirectly reducing plasma iron concentrations [ 29- 32].

This possible mechanism was explained therein according to an excessive sympathetic reaction, causing an opposite reaction to the initiated by an abnormal activation of mechanoreceptors activation, and also causing the activation of the afferent vagal fibers.

The major targets of protein phosphorylation/dephosphorylation causing the activation of sperm motility are structural components of dynein arms (inner and outer), kinases, and phosphatases anchored in the axoneme and in the radial spoke proteins (Dey and Brokaw [1991]; Hamasaki et al. [1991]; Porter and Sale [2000]; Yang et al. [2001]).

In contrast, our results clearly show that ASK1 activated by BSO causes the activation of JNK and p38.

Both pathways cause the activation of initiator caspases, which then activate effector caspases [ 21].

The caspase activity results show that ESE-16 causes the activation of caspases and reveals that ESE-16 causes cell death in a caspase-dependent manner.

Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2.

Of particular – yet unresolved – interest is how these nanoparticles cause the activation of these pathways.