Sentence examples for causing t from inspiring English sources

Marek's disease virus (MDV), the causative agent of Marek's disease (MD), is a herpesvirus that infects poultry causing T lymphomas.

So Mongkolsapaya, Gavin Screaton of the University of Oxford, and their colleagues asked whether dengue was also causing T cells, which ordinarily kill virus-infected cells, to malfunction.

Therefore, IL-10 seems to be causing T cell inhibition.

Therefore, in contrast to finding that aberrant negative selection plays a significant role in allowing the escape of disease causing T cells, we find that positive selection is a major contributor.

The specificity and affinity of self-reactive T cells is likely to impact the development of autoimmune-disease causing T cells in the thymus as well as their function in the periphery.

However, immunotherapy protocols used so far have had only a limited success what was attributed to poor recruitment of antigen specific T cells into tumor lesions, inadequate stimulation by antigens derived from tumor cells causing T cell anergy instead of T cell activation and, in particular, to the presence of regulatory T cells (Treg) expressing a transcription factor Foxp3 [2]–[4].

Consequently, partial disruption of FasL protects from autoimmune diabetes without causing T-cell lymphoproliferation.

Moreover, Sox3 was identified as a target of retroviral insertions causing T-cell lymphomas in mice [42] and the Sox2 locus is frequently amplified in prostate cancer [43].

It is upregulated in sepsis and impairs immunity by inducing apoptosis, increasing production of IL-10, preventing T-cell proliferation, and causing T-cell exhaustion.

One concern about the use of caspase inhibitors in sepsis, despite positive animal data, is the risk of causing T-cell anergy in humans.

When this chimeric receptor was expressed in T cells, upon exposure to cognate antigen and ligand binding to the variable heavy and light immunoglobulin domains, CD3 ζ signaling occurred, causing T-cell activation.