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Open image in new window Fig. 11 Contrast ultrasound agent administered through a "port-a-cath" for a malfunctioning line causing point tenderness.
Because of their well-known characteristics, the polymorphism of GSTs causing point or null mutations are often associated with certain diseases [ 2, 3].
An alternate approach is ENU mutagenesis, in which male mice are treated with the alkylating agent ethinyl-nitrosourea, causing point mutations in sperm DNA.
Acetaldehyde may promote carcinogenesis by causing point mutations, inducing sister-chromatid exchanges, impairing DNA repair, inducing metaplasia of epithelium, and forming mutagenic adducts with DNA [ 40].
AID also functions in somatic hypermutation (SHM) at Ig variable domains of the light and heavy chains, causing point mutations, some of which increase the affinity of the Ig for its antigen [ 20].
The studies reported herein demonstrate that hydroxyl radical-induced DNA damage can activate the K-ras 4B and C-Raf-l oncogenes by causing point mutations and deletions, respectively.
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Pores or cracks in nitrocellulose coatings are found to occur due to incomplete coverage, causing points of failure and corrosion pitting [13].
In 1846 the United States and Britain, acting for Canada, agreed to extend the 49th parallel as the boundary between the two countries, not noticing that this act would cause Point Roberts to be cut off from the rest of Canada.
Slightest variation in this technique causes point contact between the two major fragments.
This causes point C to move upwards, while points A and B move downwards, resulting in dorsiflexion.
NEU is known to cause point mutations which ultimately lead to the formation of mammary tumours in rat models.
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