Sentence examples for causing it to dissociate from inspiring English sources

Akt stimulates IKK to phosphorylate, which phosphorylates the inhibitory IkB protein causing it to dissociate from NF-kB, which causes its activation (Modified from Anaesth Intensive Care 2011, in press).

ROS oxidize cysteine residues of the Trx protein causing it to dissociate from ASK1 resulting in its activation through autophosphorylation.

Overall, the results support a model in which leucine selectively promotes dephosphorylation of Sestrin2, causing it to dissociate from and thereby activate GATOR2, leading to activation of mTORC1.

(IPTG is a stable synthetic lactose mimic that binds lac repressor, causing it to dissociate from DNA).

Whereas, derepression of the fructose operon takes place when cytoplasmic glycolytic catabolites, such as fructose-1-phosphate and fructose-1,6-bisphosphate, bind to the Cra protein, causing it to dissociate from the operator.

Accordingly, Choi et al (2005) have recently reported that phosphorylation of Gro by DHIPK2 causes it to dissociate from one of its DNA-binding partners, bringing about derepression of target gene expression.

Hyperphosphorylation of tau causes it to dissociate from microtubules, thereby greatly reducing their stability and ultimately leading to cell death.

In addition, Yan et al. reported Kisspeptin-10/Kiss-1R acanvation can dephosphorylate nuclear factor kappa B (NF-Kappa B), and cause it to dissociate from the MMP-9 promoter.

22 Phosphorylation of Beclin-1 by DAPK causes it to dissociate from BCL-2 family members and this event promotes the induction of autophagy.

Starvation-induced autophagy is associated with increased levels of ROS and has been shown to be mediated by the activation of c-Jun N-terminal protein kinase 1 (JNK1) which, in turn, phosphorylates Bcl-2 and causes it to dissociate from Beclin 1 (26).

The abnormally hyperphosphorylated state of Tau protein can cause it to dissociate from the microtubule and aggregate into paired helical filaments (PHFs) (Kuret et al., 2005; Mazanetz and Fischer, 2007), leading to multiple downstream events and culminating in neuronal cell death (von Bergen et al., 2005).