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VRK1-mediated phosphorylation of BAF triggers BAF release from nuclear membrane proteins that contain LEM domains, causing disintegration of the nuclear envelope during early mitosis [10].
Disruption of the envelope either by lipid attack (causing disintegration) or protein denaturation (preventing fusion to host cells) inhibits the virus being transmitted to a new host.
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I wasn't in the field the years they excavated the skeleton, but I am awed by the fact that the team was able to recover bones that were so fragile; just breathing on them would cause disintegration.
Acidification can cause disintegration of reefs even when they're otherwise healthy — but the new study is all the more concerning because the Florida reef tract has already suffered its share of stress over the past few years.
It is worth noting that in the experiment in which nocodazole treatment caused disintegration of the Golgi apparatus32, the degradation of internalized cell was not inhibited and continued after 8 h and longer exposure to drug (Fig. 6d).
Suarez's very presence can cause disintegration in defences.
Nonetheless, the gruesome duel underway between both companies' legal teams may cause disintegration within the relationship.
During ESWL, shock waves generated outside the body cross through the soft tissues without loss of strength and cause disintegration of urinary stones into smaller portions through direct shearing force, erosion or cavitation.
One more point: Change causes disintegration.
Moving too aggressively against the drug kingpins would not only risk more short-term economic pain (the kind that counts most in elections), but also would almost inevitably cause disintegration of the ruling Institutional Revolutionary Party.
To further confirm the functional requirement of kinesin-mediated transport, we generated Klc8e×94 MARCM clones, and found that loss of the Klc activity caused disintegration of the axonal bundles and aberrant dendritic overshooting (Fig. S7A F).
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CEO of Professional Science Editing for Scientists @ prosciediting.com