But even a very small number of returning extremists could cause considerable harm.
However, there have been unfortunate circumstances in which drugs have caused considerable harm.
The report documents "numerous unsafe practices and gross departures from generally accepted medical standards which have posed significant risk to patients and caused considerable harm".
In December 2013, a group of 15 doctors operating on Christmas Island revealed "numerous unsafe practices and gross departures from generally accepted medical standards which have posed significant risk to patients and caused considerable harm".
"MacDonald's zeal to advance her agenda has caused considerable harm to the integrity" of the Endangered Species Act programs "and to the morale and the reputation" of the Fish and Wildlife Service, "as well as potential harm to individual species," Mr. Devaney said in a cover letter to his report.
Cardiac diseases are the leading cause of mortality worldwide and cause considerable harm to human beings.
It may seem to be justified by the current severe shortage of organs, which causes considerable harm to patients who experience increasing ill health or who die because no transplant is available, as well as to the organ retrieval team, for whom the well-being and survival of transplant-list patients are crucial objectives.
The real risk is that the police will focus on achieving short-term targets through easy arrests of, for example, cannabis users, rather than prioritising those crimes which are much harder to detect but can cause considerable harm, such as domestic abuse or people trafficking.
But as a footnote to every major article about a major presidential candidate, I believe that this causes considerable harm to The Huffington Post as a serious media source.
High-risk prescribing in primary care is common and causes considerable harm.
A serious AE was defined as one which caused considerable harm (requiring of new treatment or prolonged hospitalisation) or irreparable damage (erroneous surgery, permanent disability or death).
