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Trypanosomiasis is responsible for many reproductive disorders in bovine herds such as the degeneration of the hypothalamus, the pituitary gland, and the gonads causing, as a consequence, alterations to the concentration of secretions and plasmatic concentrations of essential hormones for reproduction in both males and females [ 2, 10].
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"We are very very sorry for any anxiety and stress and pain it causes as a consequence of this".
Recent work has shown that the devastating symptoms of this disorder are correlated with the elevated levels of NAA observed in these patients, caused as a consequence of the inability of mutated forms of aspartoacylase to adequately catalyze its breakdown.
ConA-induced hepatitis is a well-established model for hepatitis caused as a consequence of T and NKT cell activation [14], [37].
Recently, the splitting of the resonance modes has been observed, which is caused as a consequence of clockwise and anti clockwise propagating mode coupling.
The hyperglycemia is caused as a consequence of a deficiency in insulin in type 1 diabetes (T1D), and is a feature of late type 2 diabetes (T2D) along with insulin resistance.
As shown in Figure 4b this process exhibits a fast dynamic, causing as a main consequence that the steady state for the cLIP is achieved early in the simulation.
This implies that reviewing a patient over time may cause harm as a consequence of delayed referral and subsequent diagnosis.
Another possible explanation, however, is the possibility that this increase is caused indirectly as a consequence to high levels of cytokines, as IL-10 [ 28].
R88 is the equivalent of R112 in human XPD which when mutated to a histidine results in an inactive helicase and causes trichothiodystrophy as a consequence of defective NER (Dubaele et al, 2003; Nishiwaki et al, 2004, 2008).
Importantly, hGCN5 depletion did not result in DNA damage as assessed by γH2AX formation, suggesting that the observed decreases in H3K9Ac and H3K56Ac were specific and were not caused indirectly as a consequence of DNA-damage induction (Supplementary Figures 8C and 10).
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