Sentence examples for causing an impediment from inspiring English sources

26, 27 Afatinib not only blocks EGFR but also blocks the preferred dimerization of EGFR with HER2, causing an impediment of downstream signaling, which forms an important rationale for overcoming resistance after treatment with first-generation EGFR TKIs.

The results of this study suggest that NSAIDs like ibuprofen have an inhibitory effect on the release of prostaglandins during initial tooth movement and thereby may cause an impediment in the rate of tooth movement.

The attorney general, Dominic Grieve, by not taking action in this instance, seems to have taken the view that his tweets have not caused a serious impediment to John Terry's case by influencing a witness.

The extra noise produced by changing the online user set with only one user, apparently caused a sufficient impediment for the adversary to guessing x 1.

Model results indicate that the floodplain constriction caused a significant impediment to flood conveyance at even modest discharges during prehistoric conditions.

Extensive fuel-matrix interactions leading to plate pillowing have caused a severe impediment on the development of a suitable high density low-enriched uranium dispersion fuel for high power applications in research reactors.

Oversized baby teeth and an overbite caused a speech impediment that necessitated speech therapy.

However, administration of anti IL-7 to the KO animals severely reduced their CTL response (Figure 1F) further emphasizing that the absence of both IL-7 and IL-15 can cause a severe impediment in the development of antigen-specific CD8+ T cell immunity against Toxoplasma infection.

Cho (1999, p. 3) believes that "rating discrepancy between raters may cause a very serious impediment to assuring test validation, thereby incurring the mistrust of the language assessment process itself".

A New York State policy change last year transferring 77,000 Medicaid-eligible children to Child Health Plus caused just such an impediment.

Expression of multidrug pumps including P-glycoprotein (Pgp) in the plasma membrane of tumor cells often results in decreased intracellular accumulation of anticancer drugs causing serious impediment to successful chemotherapy.