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The gene was induced by estradiol in both wt and ERβ + cells; however, expression of ERβ in the absence of hormonal stimulation induced a promoter usage switch and retention of the first intron causing an alternative translation start site and therefore the expression of an isoform with a different N-terminal sequence (ENST00000367857), compared to the major isoform expressed (ENST00000237305).
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In summary, we present data showing that the infection of N. gonorrhoeae causes an alternative amphiregulin processing, subcellular distribution and release in human epithelial cervical cells that likely contribute to the predisposition cellular abnormalities and anti-apoptotic features of N. gonorrhoeae infections.
Dopexamine caused no demonstrable increase in ileostomy blood flow, and this finding suggests that any improvement in outcome caused by the drug in the critically ill may be caused by an alternative mode of action.
Any psychiatrist who claims that a behaviour is being caused by ADHD is perpetrating a "philosophical tautology" - he is doing nothing more than telling you that hyperactivity is caused by an alternative name for hyperactivity.
This seems to be caused by an alternative compensatory mechanism because expressions of ACTH and corticosterone have been shown to be not affected in Brn-2 homozygous knockout mice despite the loss of hypothalamic neurons expressing CRH in those mice (25).
The 1.2 kb form was therefore caused by an alternative splicing.
In 59 of 230 patients (26%) without a macrovascular cause, an alternative explanation for the non-traumatic intracerebral haemorrhage was found, mainly on MRI (table 1).
In such systems, small changes or disturbances may push the ecosystem beyond a critical threshold, causing a sudden shift to an alternative state [1], [3].
The Northern Irishman has been linked with favourite Shutthefrontdoor, but Cause Of Causes is an alternative.
Indeed, the addition of a third alternative caused an increase of both absolute and relative preferences only when the asymmetrical decoy exhibits the intermediate expression of the trait initially less preferred.
More than 35 repeats lead to a toxic gain of function causing abnormal alternative splicing, a premature termination and finally truncated, inactive muscle-specific chloride channels (CIC-1) as well as a defective calcium reuptake pump of the sarcoplasmatic reticulum (SERCA1) [ 3, 4].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com