Sentence examples for causing a gain from inspiring English sources

This was an unexpected result and implies that the PKA binding site mutation in the D36 animals is causing a gain of function effect on synaptic plasticity which is not seen when the protein is eliminated in the KO.

What is clear is that miRNA-1253 may have an important role in MB cells, negatively regulating an antagonist of the positive effects of the differentiation factors BMP2 and BMP4, thus causing a gain of function such as MB cell proliferation.

As it stands, late-onset diseases are mainly protein-folding diseases, with the accumulation of protein deposits causing a gain-of-function proteotoxicity [ 79].

Late-onset diseases such as Alzheimer's disease, Parkinson's disease, or frontotemporal lobar degeneration are considered to be protein-folding disorders, with the accumulation of protein deposits causing a gain-of-toxic function.

(Theoretically 3,500 extra calories cause a gain of one pound).

The first common functional trait identified so far, in four of these mutants, is an increased sensitivity to the acetylcholine, suggesting that these mutations may cause a gain of function.

The rising B content caused a gain in h-TiB2 phase fraction, which strongly affects the residual stress provoking a change from ~ 1 GPa tensile to ~ 1 GPa compressive across the coating thickness.

Xist expression in the absence of silencing does not reduce H3K4m2 or H3Ac at promoter regions or cause a gain of DNA methylation.

As a consequence, this causes a gain in life years and QALYs compared to current practice scenario (no provision of SBI). Figure 1 displays a costs (differences in intervention+lifetime health care costs) and effects (QALYs gained) plane for SBI scenario compared to current practice scenario, for different values of the model input parameters.

These mutations may cause a gain of function.

It has been proposed that its mutations could cause a gain of toxic function [147].