Exact(11)
Table 2 Sequentially listed filtering steps for homozygous analysis ROH Rare functional variants (RFV) 5 Non-synonymous coding, indels 4 RFVs in good sequence quality (Q > 100) 4 RFVs not reported in dbSNP database 2 Non-reported RFVs predicted to be disease causing 1 ROH regions of homozygosity.
As late as August 5, yet another aftershock of 6.1 Ms (6.2 Mw according to USGS) hit Qingchuan, Sichuan, causing 1 death, 32 injuries, telecommunication interruptions, and widespread hill slides blocking roads in the area including a national highway.
The isolated SW PB1 [accession number HM849035] contains 3 mutations of G1299A, A1303G and A1758G (counting from the A of the initiator ATG as nucleotide 1) compared to the sequence of A/California/04/2009 PB1 [accession number FJ966080] [8], [8], causing 1 coding change of I435V.
Cancer is a major public health problem worldwide, causing 1 in 4 deaths in the United States [ 1].
In 1991, it appeared unexpectedly in Latin America, causing 1 million reported cases and 9,170 deaths in the first 3 years (2 ).
Coronary heart disease is the commonest cause of death in the UK, as a consequence of acute myocardial infarction (AMI) causing 1 in 5 and 1 in 7 deaths in men and women, respectively (http://www.heartstats.org).org
Similar(48)
Malaria is caused by Plasmodium species and infects several hundred million people annually, causing 1 3 million deaths.
Malaria remains a major parasitic disease in the tropical and sub-tropical countries causing 1 2 million deaths globally every year.
The p.Gly375Asp mutation is predicted to be damaging by prediction programs (Polyphen‐2: probably damaging [1], SIFT: damaging [0], MutationTaster: disease causing [1]).
Atypical pathogens have been the major cause of CAP in some studies from the west with Legionella pneumophila type 1 causing 1-30% [ 5, 13, 14] of adult cases and Mycoplasma pneumoniae being implicated in 20-30% [ 15, 16] as an etiological agent.
This patient had a history of endocrine and non-endocrine malignancies: at age 67 she was admitted for surgical resection of multiple typical bronchial carcinoids and a subcutaneous epigastric lipoma, and she was subjected to left parathyroidectomy because of a parathyroid adenoma causing 1°HPT.
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