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And it remains to be seen whether long-term activation of the channel causes toxic effects in cells.
Pollution, which is caused by the spilling of commercial petroleum fuels (CPFs), is a major environmental constraint that causes toxic effects in aquatic ecosystems.
High concentration of solubilizers in its formulation causes toxic effects and allergic reactions [ 10].
But paradoxically N9 fails to protect women against HIV and other STD pathogens, most likely because it causes toxic effects that increase susceptibility.
It is noteworthy that most of the previously reported functions of hCDC14A/B were deduced upon siRNA depletion (often without a rescue experiment) or strong over-expression that causes toxic effects.
One of these compounds which increases the activity of Nrf2 and not causes toxic effects on NIH3T3 cells is 3,3-diindolylometan which is derived from indol-3-carbinol fermentation [ 20].
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Moreover, it is clear that long term exposure to Cd and Pb contamination causes toxic effect in the liver.
As an ultra-trace nutrient, arsenic deficiency leads to inhibited growth, although beyond its necessary level it causes toxic effect on plants, animals, and human beings.
Additionally, residues may be present in the bodies of rodents which could cause toxic effects to scavengers and predators.
Xenobiotic organic compounds (XOCs) in wastewater treatment plant (WWTP) effluents might cause toxic effects in ecosystems.
The residues of azole fungicides could cause toxic effects on aquatic organisms such as algae and fish.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com