Sentence examples for causes substantial changes from inspiring English sources

Using UV visible spectrophotometry, we show that the removal of K+ binding site causes substantial changes in spin states of both the ferric and ferrous forms.

This causes substantial changes in the forcing coming from OP, with an amplitude of around 4 W m−2 in the 10,800-day average when the eccentricity is small (approximately 0.01), to around 15 W m−2 when the eccentricity is large (approximately 0.023) (Fig. 5).

A potential drawback of replicating virus-based expression systems, which has to date received little attention, is that expression of viral proteins [7], as well as the regulation of host proteome associated with viral replication [8], [9], causes substantial changes to the host cells.

It is of interest that the Fusarium infection of chickpea causes substantial changes in the expression of numerous unknown transcripts yet to assign a cellular function.

A phase I clinical study by Zafar et al. showed that edoxaban causes substantial changes in INR, prothrombin time (PT), anti-factor Xa activity and activated partial thromboplastin time (aPTT).

Hurricanes making landfall can cause substantial changes in the sediments deposited in inland basins.

Mr. Hearn said the loss of the Wendy's account would cause "substantial changes" at Bates that could include layoffs.

The results demonstrate that different hand postures cause substantial changes in hand geometry, especially in the metacarpal region.

Subsequent removal of the residual stands may cause substantial changes in understory vegetation for the whole treatment area.

We hypothesized that road development is a key driver of land-cover change and will cause, substantial changes in areas of forest cover, cultivated food and cash crops.

This activity severely affects the structure and balance of the natural ecosystem, and also has the potential to cause substantial changes in landscape geochemistry.