Sentence examples for causes significant difficulty from inspiring English sources

This phenomenon, in fact, causes significant difficulty for perfumers.

This causes significant difficulties with the convergence of finite element solutions.

However, the asynchronous nature of an infection causes significant difficulties in determining host genes responsive to a single viral gene product.

The charter provided for the college to operate at both Canonsburg and Washington, a position that caused significant difficulty for the administration trying to rescue the college amid ill feelings over the unification.

The high prevalence of overlapping diseases (such as pneumonia, malaria and malnutrition), and the difficulty in creating reliable diagnostic algorithms to identify eligible populations cause significant difficulty in the application of disease-specific models.

This project has in recent years inadvertently caused significant difficulties in forming a stable, collaborative, national government, a stasis that grieved his generation.

Interactions between process units (e.g., material recycle and energy integration) often cause significant difficulties in plantwide control.

Later the same year, Scotland's Chief Inspector of Constabulary warned the sheer scale of Ore was causing "significant" difficulties for forces.

The poor quality of communication between professionals, perhaps reflecting a limited understanding of the various roles in patient care, we found to cause significant difficulties.

In combination with other health issues (e.g. limited mobility and managing diabetes) this mild memory problem caused significant difficulties and concern.

In cheese factories, delays to fermentation can cause significant difficulties in a process that is based on a perishable starting material (milk) that cannot be stored in the event of delay.