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Further investigation indicated that the elevated expression of 14-3-3σ 14-3-3σ 14-3-3σcausesanticanceresistance resistong drug-induced anticancerandrugsucing cell cycle arrest for repair of DNA damage [ 9, 10].
Disruption of Msh6 causes resistance to 6-TG72, and was used as surrogate for Cas9 activity.
Noise is resistance, or at least it causes resistance, so can never be the mainstream.
Disruption of Hprt causes resistance to 6-TG4, and selection with the drug allowed faster identification of double-mutant cells.
Zhang, Z. et al. Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer.
D.C. wrote the manuscript with input from P.A.K. and A.D.D. Extended Data Fig. 1 depletionpletion causes resistance to PARPi and cisplatin in multiple lineages.
Zhang Z, Lee JC, Lin L, Olivas V, Au V, LaFramboise T, et al. Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer.
Subsequent studies by members of his group have found that interfering with MED12 messengers causes resistance to numerous other drugs.
"Art in the public domain is always a conflict and causes resistance," Mr. Lüpertz said at the time.
Continuous use of chemical larvicides causes resistance in many species around the world and also environmental pollution.
Resistance is due to mutations in 23S rRNA and the ribosomal proteins L3 and L4 and, more recently, the mobile cfr gene (causes resistance to several antimicrobial classes).
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