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Less common causes of switching from PD to HD included abdominal surgery, pancreatitis/malnutrition, decreased mental capacity and abdominal wall defect (Table 2).
BGJ analyzed and interpreted the data, reviewed medical records for causes of switching from peritoneal dialysis to hemodialysis, drafted and revised the manuscript for important intellectual content.
DCC reviewed medical records for causes of switching from peritoneal dialysis to hemodialysis and revised the manuscript for important intellectual content.
Previous studies have shown that the main causes of switching from PD to HD were infections, fluid overload, abdominal surgery, malnutrition, decreased mental capacity and abdominal wall defect [ 34].
However, compared to administrative data, our study provided the advantage of a prospective incident cohort with detailed data on comorbidities, laboratory values, and access to patient charts to determine specific causes of switching.
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Infectious peritonitis was the leading cause of switching.
Infections (peritonitis and catheter-related) (36.9%) were the leading cause of switching from PD to HD, followed by cardiovascular (fluid overload) causes (18.5%).
Over the past decade, very few studies in the United Sates have analyzed both the cause of switching from PD to HD and the timing of this switching process after initiation of PD.
In agreement with previous studies, we found that infections remain the leading cause of switching from PD to HD, followed by cardiovascular causes, mainly fluid overload [ 9, 17, 23].
In the present study, data from patients with technique failure showed that peritonitis was the major cause of switching to hemodialysis, and that there was no difference between the two groups.
Causes of switch from PD to HD were ascertained from comprehensive chart review.
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