Sentence examples for causes of compound from inspiring English sources

In addition, cardiac toxicity as a result of drug therapy is one of the main causes of compound attrition during drug development and post-marketing withdrawal.

Incorporation of cFLIPL into the ripoptosome could thus be a cause of Compound A resistance in CLL cells.

Concerns over cardiac side effects are the largest single cause of compound attrition during pharmaceutical drug development.

There is historical precedence that industry can identify and remedy significant causes of attrition; inadequate drug metabolism and pharmacokinetics are no longer the primary cause of compound attrition.

But the substantial form of a material compound, because it is predicated (accidentally) of the matter of the compound, is the cause of the compound's being the kind of thing that it is.

These are: Dravya, or substance, the substratum that exists independently of all other categories, and the material cause of all compound things produced from it.

We believe that a conformational change in the MT polymers caused by binding of compound B to the colchicine pocket in the αβ-tubulin dimer may have prevented the association of the proteins with the MT surface.

Higher amounts of compound causes that damage in oocysts is not accurately observable; lower amounts extends the time of observation and damage is barely noticeable in a determined period of time.

b Type of compound causing the osmotic stress.

If the treatment of compound obviously causes the accumulation of virus at the host membrane region, this compound is believed to inhibit the entry of virus.

Numerous examples include the identification of compound heterozygous causes of diseases, including the gene that encodes protein C in cerebral palsy [ 84], Charcot-Marie-Tooth neuropathy [ 85], and the gene encoding lysyl-tRNA synthetase in peripheral neuropathy [ 86].