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The altered cytokine levels and subsequent changes in airway redox status lead to goblet cell metaplasia, transforming airway epithelial cells into mucus secreting cells, which release overwhelming amounts of mucin, especially mucin5AC, which obstructs the smaller alveoli and causes obstruction in breathing in asthma [5] [10].
The lesion that causes obstruction specifically in this particular area is the colloid cyst [21].
Thus, it has been proposed that accumulation of sequestered IRBC causes obstruction of brain microvessels leading to decreased blood flow, hypoxia, hemorrhages, coma and death [10].
BDI causes obstruction of bile ducts, which results in cholestasis.
In the respiratory tract, this molecular defect causes obstruction of the airways by mucus and chronic endobronchial infection.
Incresead concentration of 5-FU upon systemic administration of TS-1® causes obstruction of lacrymal apparatus [ 7].
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Lymphoid hyperplasia, a rapid increase in the production of white blood cells known as lymphocytes, which may be associated with viral illness, can also cause obstruction.
Stent migration may cause obstruction of the bowel lumen.
Either physical or chemical processes may cause obstruction of the conduit.
Perioperative airway assessment is particularly important in patients with congenital anomalies that may cause obstruction.
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