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The high number of children exposed causes major concern and has important implications.
Among the factors, which have been hindering cattle production in Mozambique, mortality of calves is one that causes major concern.
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The high prevalence of mental disorder among adolescents in RYC (76.2 %) causes major concerns and challenges the existing organization of the RYC system.
The upgrade has caused major concern within the arms-control community.
Earlier this year, during Malta's presidency of the European Union, her revelations caused major concern in Brussels.
This apparent backtracking caused major concern in the West (particularly in the United States and Russiaa.
Heavy metal contamination of soils resulting from mining and smelting is causing major concern due to the potential risk involved.
The office's activities, disclosed last Tuesday by The New York Times, caused major concern among Bush administration officials traveling with the president in Asia.
But the explanation of the timing and editing of the front-page article by James Risen and Eric Lichtblau caused major concern for scores of Times readers.
The most recent August print was relatively strong but not enough to cause major concern.
City's erratic results under former boss Derek McInnes caused major concern among the Robins faithful.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com