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Diabetes mellitus causes imbalances and pathological changes in several tissues.
Furthermore, recent molecular analyses suggest that the pathognomonic FOXL2 mutation causes imbalances in transforming growth factor (TGF)- β signaling, and more precisely, impaired interaction with SMAD transcription factors 42, 43.
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2. Hustling causes imbalance.
With OA progression, excessive catabolic activity causes imbalance of cartilage homeostasis and cartilage matrix breakdown.
Hyper physiological burden of free radicals causes imbalance in the homeostasis between oxidants and antioxidants in the body.
Endothelial dysfunction causes imbalance of the vasodilator system's homeostasis especially involving the production and metabolism of NO [ 12].
Recent studies revealed that exposure to EDCs causes imbalance in prooxidant/antioxidant levels and thereby promotes the generation of ROS [ 31, 32].
"The unfortunate irony is that drugs heavily promoted as correcting unproven biochemical imbalances may be, in fact, causing imbalances and brain damage," he asserts.
The chairman of the House Ways and Means trade subcommittee, Representative Sander Levin of Michigan, said after the report was issued that he felt some countries were manipulators and had caused imbalances.
The disadvantage is that it will cause imbalances in the categories, which greatly affect classification accuracy.
Dehydration does certainly cause imbalances in the body, particularly of fluids and salt, says Goldfarb, but dehydration affects the whole body, not one localized muscle.
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