Sentence examples for causes discontinuation from inspiring English sources

Neurotoxicity is the greatest concern regarding BV, and the most frequent complication is peripheral neuropathy (PN), which often causes discontinuation of therapy.

Less than one-half of these patients discontinued minocycline or doxycycline because of side effects, suggesting that they are at least as well tolerated as other second-line RA medications, for which drug toxicity causes discontinuation in 15% of all patients [ 35].

Overall acceptability Overall acceptability The acceptability of treatment will be defined as all-cause discontinuation, as measured by the proportion of patients who discontinued treatment (during the delivery of the intervention) up to the post-intervention time point.

We report about all adverse events causing discontinuation earlier than 180 days.

The most common side effect that caused discontinuation within 1 year was irregular bleeding.

Although adjunctive armodafinil compared with adjunctive placebo yielded a higher headache rate (15 vs 8%%), it yielded similar (generally favorably low) rates of all-cause discontinuation (16 vs 16%%), adverse event discontinuation (4 vs 5 %), nausea (6 vs 4%%), ≥7 % weight gain (2 vs 5 %), anxiety (4 vs 3 %), insomnia (3 vs 2 %), sedation/somnolence (1 vs 1 %), and hypomania (0 vs <1 %).

Anxiety and bipolar I disorder were the only AEs that caused discontinuation in >1 patient; anxiety led to treatment discontinuation in 3 (2 %) of those treated with adjunctive armodafinil and 0 treated with adjunctive placebo; 2 patients taking adjunctive armodafinil and 0 patients taking adjunctive placebo discontinued due to bipolar I disorder.

Among responders to CBZ, 27% of patients incurred in adverse events that directly caused interruption of treatment by the physician or a dosage reduction to a level that was insufficient to control pain, thus causing discontinuation, after a mean period of 8.6 months.

All-cause discontinuation was used as a measure of acceptability.

The time to all-cause discontinuation was shorter on both doses of LY2140023 than on placebo.

The association may also be confounded if manifesting symptoms cause discontinuation of vitamin D supplementation.