Exact(9)
Transient ERM knockdown by RNAi causes disassembly of actin stress fibers and focal adhesions, a decrease in the cell stiffness, and membrane separation from the cytoskeleton.
HPT also sequesters normal tau and other microtubule-associated proteins (MAP1 and MAP2) and causes disassembly of microtubules[13].
In addition, SIL causes disassembly of the vimetin cytoskeleton, possibly via phosphorylation of the vimentin.
SIL also causes disassembly of the vimentin intermediate filament cytoskeleton as detected by immunofluorescence.
Dephosphorylation of occludin causes disassembly of its association with ZO proteins.
Our data suggest that palmitate causes disassembly of the tight complexes of Ca2+ channels and weakens the Ca2+ microdomains that form and trigger insulin exocytosis.
Similar(51)
Thus each of the between-dimer mutants caused disassembly when added to wild type polymers.
Consequently, decreased expression could cause disassembly or a reduction in the number of hemidesmosomes, with failure of cell anchoring.
However, not all XPG C-terminal truncations in XPG/CS cells cause disassembly of TFIIH and CAK (Table 1).
Colchicine (1 μM; 45 min) was used for the disassembly of microtubules, whereas latrunculin B (5 μM; 45 min) was used to cause disassembly of F-actin.
Mutations of lamin A/C (Lmna) gene or the Zmpste24 gene produce abnormal lamins, such as progerin or prelamin A, respectively [ 16], which can cause disassembly of the nuclear envelope proteins, subsequently accompanied by accelerated aging due to laminopathies [ 16].
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