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An increased angiotensin II level causes deleterious effects on renal haemodynamics and induces the expression of different growth factors and cytokines, leading to tubulointerstitial fibrosis and glomerulosclerosis [14].
However, constitutive overexpression of ERF genes generally causes deleterious effects.
This activates the proinflammatory transcription factor nuclear factor-κB (NF-κB), which causes deleterious effects.
Whether iron therapy causes deleterious effects in paediatric HIV infection has not been established.
However, astrocytic NF-κB activation also causes deleterious effects by increasing excitotoxicity [ 1] and hampering neurite outgrowth [ 15].
The presence of extracellular gal-3 in the vicinity of chondrocytes and osteoblasts causes deleterious effects by both downregulating the anabolic processes and upregulating the catabolic processes.
Similar(51)
Solar irradiation induces skin inflammatory processes causing deleterious effects like premature ageing.
Large volume infusion for the achievement of profound hypothermia may cause deleterious effects of increased ICP and is not warranted.
Timber harvest often results in accelerated soil erosion and subsequent elevated fine (< 2 mm) sediment delivery to channels <span class="lh lhl">causing deleterious effects to numerous aquatic species, particularly salmonid fishes.
Movement restriction results in a greater amount of inbreeding, which can cause deleterious effects leading to a population bottleneck, whereby a significant percentage of the population is lost.
These data support the notion that expanded CAG repeat RNA can cause deleterious effects in mammals.
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