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However, the complexity of the ubiquitin system causes considerable challenges for high-throughput drug discovery because of extensive structural similarities.
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If XDR-TB became widespread, its severity and the difficulty of case management and infection control could cause considerable challenges for global public health.
In comparison, the 2008 Wenchuan Earthquake generated more than 250 landslide dams, but the largest of these at Tangjiashan, which causes considerable hazard management challenges, impounds a lake volume three orders of magnitude smaller than the Jinsha landslide dam [17, 18].
The Senate Democrats have considerable challenges.
Bacterial contamination is one of the major challenges for yeast culture because it causes considerable economic losses by competing for substrates and inhibiting yeast cell growth [ 22].
This constitutes substantial challenges for the health care system and also causes considerable direct and indirect costs.
Thus it constitutes a substantial challenge for the health care system and causes considerable direct and indirect costs [ 3].
It's a subject that causes considerable angst in Tchula.
This causes considerable difficulties in plantwide control.
ISH causes considerable tissue section shrinkage (80%).
Hypertension causes considerable morbidity and mortality worldwide.
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