Using peptides designed as mimics of HMGR substrates, and a combination of in vitro test and circular dichroism study, it was found that: (1) peptide binding causes an ordering of secondary structure, reflecting an increase of α-helical content; (2) HMGR binds the peptide without closure of the active site; and (3) peptide binding induces the protein aggregation.
Loss of APC function causes an order-of-magnitude increase in the crypt fission rate and demonstrates a critical role for APC in regulating growth.
In any event, a child just yelling "Batman" to Alexa wouldn't cause an order to be placed.
However, volume-equivalent single particle models (Rayleigh/Mie) overestimated dp by about a factor of 3, causing an order of magnitude underestimation in np.
A different combination of fuel utilization, anode Pt loading and flow channel design can cause an order of magnitude difference in CO tolerance under identical experimental conditions of temperature and current density.
Factors beyond the control of the shipper such as a natural disaster may cause an order to be delivered several days later than originally anticipated.
Only one segment from variant 13 remained unfixed and, during consensus analysis, caused an ordering error in set 1. Thus, only one out of 28 segments remained uncorrected.
Such a theorist can and perhaps should—insist that phenomenally conscious experience occurs when and only when a first-order perceptual state causes a higher-order belief in the existence of that state in a way that doesn't depend upon self-interpretation.
Alternatively, if a higher-order thought is causally involved it might be that a top-down expectation of pain causes a first-order experience of pain, as opposed to being constitutive of the feeling of pain.
A contact between the tool and the sample surface causes a significant (an order of magnitude or more) increase in cantilever vibrations at the first resonant frequency and thus, can be detected.
