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23 This variability causes additional difficulties in the estimation of GFR.
The frequent lack of a unique universal identifier causes additional difficulties because the quality of electronic record linkage procedures is always less than perfect.
Chronic alcohol use probably causes additional difficulties [ 9]: tachycardia and delirium due to withdrawal complicating administration of atropine, and alcoholic myopathy increasing the risk of cardiac complications from atropine therapy.
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The depression caused additional difficulties in travel and communications.
Participants reported a number of medication-related cognitive impairments, which caused additional difficulties in everyday functioning.
In addition, the processes and outcomes of the attribution of costs in NHS research have caused additional difficulties for researchers.
Mechanical ventilation may result in turbulent gas flow secondary to high gas velocity which may cause additional difficulty achieving adequate ventilation.
The government's approach causes additional problems.
Tobacco smoking causes additional exposure to polonium.
This causes additional stress on the spine.
Obviously, the Neumann boundary value conditions will cause some additional difficulties in establishing the a priori estimates (see for instance [26, 28]), which will be the topic of our further work in the future as well as the corresponding problems with Dirichlet-Neumann boundary conditions.
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