Sentence examples for causes a substantial problem from inspiring English sources

This failure causes a substantial problem when trying to estimate the overall rates of mental health problems.

IBS causes a substantial economic burden.

Each year influenza causes a substantial burden of illness.

Seasonal influenza causes a substantial burden of illness worldwide.

"They cause a substantial trash issue and health problems at our beaches and parks".

"It could become a substantial problem," he said.

"It's a substantial problem," Botstein recognized.

Neurological complications of paediatric cancers are a substantial problem.

Low patient adherence is a substantial problem in therapy.

Bullying in school is a substantial problem for Greek youth.

Publication bias is a substantial problem throughout science.