Exact(1)
The ddm1 mutation in Arabidopsis, which results in genome-wide methylation reduction by 70% [ 34], has caused transposition of an otherwise dormant endogenous CACTA transposon, and produced a spectrum of new insertions [ 31].
Similar(59)
Retroelements in rRNA sequences may cause transposition of rRNA sequences.
Small-scale duplications may also cause transposition of one of the duplicate genes to an ectopic site.
Hypomethylation in the promoter region of LINE-1 causes transcriptional activation of LINE-1 element, which causes transposition of the retroelement and chromosomal alteration [ 21].
A model is described of DNA re-replication mediated by the alternative transposition of Ac/fAc, which in addition to other well-documented chromosomal rearrangements caused by transposition, may have contributed to the dynamics of gene creation and genome expansion.
In addition, some virulence genes are regulated by transposition [ 44] and it is proven that some insertions, deletions, inversions and chromosome fusions are caused by transposition [ 45, 46].
Gene movements are often caused by transposition.
Traces of mutations and/or genome rearrangements caused by transposition of these elements have been detected in our preliminary analysis.
In the H. sp. NRC-1, due to genetic instability caused by transposition of insertion sequences, typically about 1% of colonies in a plate are gas-vesicle deficient and 0.1% are carotenoid deficient mutants [ 13].
The dominance of the ancestral 2n = 50 karyotype in Nemacheilidae refutes chromosomal rearrangements as the trigger mechanism for this dispersion, but amplification and dispersion of 5S rDNA clusters may also be caused by transposition and unequal crossing-over or ectopic recombination between various tandemly-arrayed sequences in adjacent heterochromatin [ 102, 115, 116].
Even though transcription of TEs is not sufficient to cause their transposition, it is a necessary first step for mobilization of retroelements.
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