The phrase "caused serious concern" is correct and usable in written English.
You can use it when referring to a situation or event which has led to worrying or anxiety. For example, "The rising number of cases of the virus caused serious concern amongst the population."
The mosquito-borne virus that has spread across many countries in South and Central America has caused serious concern in Brazil.
The successful 2012 satellite launch caused serious concern but experts stressed that it lacked the re-entry technology needed to bring an ICBM down on to a target.
The U.S. State Department responded quickly that the Russian move in the quasi-annexed Georgian regions was a violation of Georgian territorial integrity that caused "serious concern".
Fighting in the Syrian capital has also caused serious concern – when rebels entered the Old City in 2012, the government shelled it.
It caused serious concern for the families of the girls, because they immediately thought it was going to be some gruesome reconstruction of their daughters' lives, which they had no idea was happening.
The US said China's lack of openness caused serious concern for other nations in the region.
It has also caused serious concerns about air quality.
Most types of bird flu are harmless to humans but two types, H5N1 and H7N9, have caused serious concerns.
"There have been several significant incidents in this building during the past few days, which have caused serious concerns to police and local residents," Superintendent Ian Wylie said.
The methods used to bolster that cushion have caused serious concerns among the companies' regulator, outside auditors from Morgan Stanley brought in by the Treasury Department and some investors.
The east European state's foreign minister told the Observer that talk of extending restrictions on its citizens to work in the UK had caused "serious concerns".
