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Severe CAA as uniquely observed in late-stage TG arcAβ mice (Fig. 10b) caused not only such strong laminin up-regulation in the VBM but lead to rupture of the vessel wall as well (Fig. 10b, arrow).
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APE1, as well as OGG1 and MPG, act to repair oxidative DNA damage, which is caused not only by agents such as tobacco smoke and heavy metals, but also by internal processes, primarily inflammation (43 45), and therefore inter-individual differences in DNA repair activities may play an important role in other cancer types.
Expression of EAT-4 in AWC and RIA (eat-4 (AWC+, RIA+)) caused not only the larger change, such as eat-4 ky5) eat-4 ky5eat-4; 10.6±1% at 90 s), but also faster change of FRET ratios in AIY (5.1±0.7% at 45 s; Figure 4A and B).
Such generalization caused not only an overestimation in the maximum power delivered to the load resistance for cases (I) and (II), but also an underestimation of the optimal load resistance and an overestimation of device natural frequency for case (II).
Physical symptoms are caused not only by the physical demands of combat, such as carrying heavy equipment, but also by psychosocial and environmental factors [ 45, 46].
They are caused not only by osseous destruction, but also by tendinosis and consecutive tendon rupture, which are not detectable by conventional imaging such as radiographs.
Kanbay and colleagues [ 2] recently summarized the emerging data suggesting that hyperuricemia may cause not only atherosclerosis in the macrovascular beds such as the coronaries and the carotids but also microvascular damage in the renal vascular bed and may exacerbate vascular disease.
Light causes not only vision, but also non-visual effects such as regulating the circadian system.
The reduction of wasted resources, as a consequence of such investments, would cause not only widespread productivity gains, but also more robust private investment in other sectors.
Result shows that increasing level of air pollution causes not only respiratory diseases but also deaths related with such diseases increasing.
In particular, the presence of small casting defects such as micro-shrinkage cavity can frequently cause not only significant deterioration but also large scatter in fatigue strength.
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