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Myelosuppression caused modification of treatment in 14 of 108 chemotherapy cycles (13%).
Both doses tested (25 and 250 μg/kg) caused modification of the expression of similar clusters of genes (e.g. several differentiation markers, immune-related genes) that have also been reported as differentially modulated by BBP exposure in this work.
We injected aPC as a single intravenous bolus since administration by infusion would have needed the placement of a catheter in the anesthetized rabbits, and this procedure would have caused modification of the haemodynamic condition.
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We observed that silencing of KGFR caused modifications in the physiological behavior of the tested cell lines.
However, inability to replicate these results caused modifications of the protocol in our series.
It was found that this compound also caused modifications of BimEL, similar to the effects of the garlic extract.
Additionally, poor nutritional status caused modifications to the enzymatic antioxidant systems, with a lower ability to reduce oxidative compounds and a state of lipid peroxidation [ 29].
The experience gained during the pandemic may have caused modifications and improvements of procedures and capabilities, not registered in our data.
High DC biases were found to cause modification of the surface of any subsequently deposited film (either low or high density).
These effects are of high amplitude, short duration local acceleration, localized degradation of stiffness and strength in affecting members and cause modification to the overall dynamic response of structures.
Generally, these differences didn't cause modification in consensus deduced aminoacid sequence.
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