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Consistent with these features, 5'Nuc potently inhibited ADP-induced thrombocyte aggregation and even caused disaggregation of ADP-triggered human platelets.
Similar as for total tsetse fly saliva, the recombinant protein inhibited ADP-induced platelet aggregation and even caused disaggregation of thrombocytes in a dose-dependent manner (Fig. 8A).
Incorporation of amino acids into rat liver proteins was inhibited by 1,2-dimethylhydrazine, which also caused disaggregation of hepatic polysomes.
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Microorganisms may cause disaggregation of minerals through colonization and physical penetration of the mineral surface [ 35].
Conversely, knowing which residues comprise the SEM1 86 107) fibril core will allow for the design of specific inhibitors of SEM1 86 107) fibril formation or compounds that cause fibril disaggregation.
Calcium loss from the ZG causes their disaggregation, which is necessary for the secretion of digestive enzymes to the duodenum, but in excess leads to their premature activation and ultimately to necrosis [ 7].
One study failed to demonstrate the effectiveness of post-etching ultrasonic cleaning [35], although this can be explained by the fact that specimens were placed in the ultrasonic bath for 20 min, which may have caused weakening or disaggregation of the etched porcelain.
These functional data establish this experimental system as one in which neuronal development and function can be studied without animals, and without the cellular trauma caused by tissue disaggregation.
Interference with protein disaggregation caused the mislocalization of P-body components to stress granules, suggesting that P-body proteins and potentially many other proteins can enter into a stress granule state, but are normally prevented from doing so through molecular chaperones such as Hsp104.
We hypothesize that this slow disaggregation of the large colloid aggregates caused the second colloid release peak as the smaller colloid aggregates could pass through the narrow neck of the soil pore space.
Disaggregation of root tip cells might be caused by the continued expansion of the stele and a rigidification of the roots.
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