Sentence examples for caused by sequence variations from inspiring English sources
The high expression levels of Gilz mRNA can also be caused by sequence variations in the 3'UTR, the promoter region, or any other region affecting transcription and translation efficacy, promoter activity or exon splicing.
We report that inhibitors with a diacetylene scaffold effectively overcome the resistance caused by sequence variation in the LpxC substrate-binding passage.
The 2-target format provides simultaneous confirmation of P. aeruginosa identity where both the ecfX and gyrB PCR reactions are positive and may also reduce the potential for false negatives caused by sequence variation in primer or probe targets.
Collectively, these diverse mapping data sets demonstrate that expression of Comt is strongly cis-regulated and is caused by sequence variation in or around Comt itself.
The cis-eQTLs is likely caused by sequence variation around the region of the gene itself, e.g. a promoter polymorphism that gives rise to differential expression of the gene in the two parents.
From these results, we can estimate the number of putative false positives and false negatives that might have been caused by sequence variation.
A typical de Bruijn graph-based assembler will try to find and remove branches that are caused by sequencing errors (red vertices), find and collapse 'bubbles' caused by sequence variation (green vertices) and attempt to resolve branches caused by repeats (blue vertices).
The variation in fluorescence signal over the DNA molecule corresponds well with that obtained by confocal microscopy, demonstrating the viability of STED for imaging single DNA molecules and a future potential use for comparison of signal variations caused by sequence specific dye binding or partial melting.
On the other hand, true editing events are often hidden in a background noise caused by sequence errors, mapping errors and genome variations, including genomic single nucleotide polymorphisms (SNPs) and somatic mutations.
Short low-depth tips and bubbles that were caused by sequencing errors or genetic variations between microbial strains were trimmed and merged, respectively.
To improve the ability to detect SARS-CoV safely and reduce the risk of eliciting false-negative results caused by genome sequence variations, we established three individual real-time RT-PCR assays.
