Sentence examples for caused arrest from inspiring English sources

Tangeretin caused arrest of the cell-cycle progression at the G1 phase and growth inhibition in the incubation of colon adenocarcinoma COLO 205 cells [35].

Depletion of RPS13 caused arrest of parasites in the G1 cell cycle phase, thereby stopping parasite proliferation.

As shown by FACS analysis of PI labelled cells, 0.25 µM doxorubicin did not increase the sub-G0 phase that is typical of apoptosis, but it decreased the number of S-phase cells by 66%, caused arrest in G2/M and confirmed the 2-fold increase in hyperploid cells (>4N phase) (Fig. 7A).

The results showed that there were 63.3% of the cells in G1, 32.1% in S and 4.6% in G2 in 1A6/DRIM depleted cells, while there were 51.6% of the cells in G1, 38.4% in S and 10.0% in G2 in a control siRNA treated cells suggesting knockdown of 1A6/DRIM caused arrest of cells at G1 (p<0.05).

This indicated that high density suppresses geroconversion regardless of whether p21 or p16 caused arrest.

DOMINO1 plays a role in ribosome biogenesis, and its loss-of-function mutation caused arrest of embryogenesis [ 26].

This is important for two reasons: DNA breaks activate checkpoints that cause arrest of cell division, and DNA breaks engage repair machinery.

Thus, it was of interest to determine whether abrogating ribosome function might cause arrest in G1 of the cell cycle.

To cause arrest of cancer cells, we induced ectopic p21.

This predicts that any mutant p53 that cannot cause arrest will not cause senescence too.

Mutant p53 (p533KR) that cannot cause arrest, senescence and apoptosis still suppressed tumors in mice [ 2, 3].