Based on estimations of the primordial mass required to form Uranus and Neptune, as well as bodies as large as Pluto (see below), earlier models of the Kuiper belt had suggested that the number of large objects would increase by a factor of two beyond 50 AU, so this sudden drastic falloff, known as the "Kuiper cliff", was completely unexpected, and its cause, to date, is unknown.
Unilateral renal hypo/aplasia is usually sporadic and relatively common, with no genetic cause to date identified.
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"Substantial disruptions have been caused to date and there is a reasonable expectation that those disruptions to the learning and living environment would continue and may possibly escalate if he is allowed on campus," Delaney wrote.
Thirty-three unique TRPV4 mutations have been found to cause SD to date [1], [2], [3], [4], [5].
For this patient, other causes for anemia (e.g., drug-induced hemolytic anemia, digestive malignancies, viral causes known to date, hematologic malignancies, and autoimmune disorders) were excluded (2 ).
In addition, Europe, the US and other developed countries have contributed a disproportionate share of the historical emissions that have caused the warming to date and will remain in the atmosphere for decades or centuries to come.
Plague has caused three pandemics to date, which together killed about 200 million people.
These problems have caused the losses to date and they continue.
In comparison, the current outbreak of a novel H1N1 viral strain, which has become a major global issue since April of 2009, has affected 177 countries, including more than 182,166 people, and caused 1,799 deaths to date [4].
