Sentence examples for cause significant alteration from inspiring English sources

Cypermethrin was also reported to cause significant alteration in the levels of ammonia and urea in freshwater fish, C. mrigala (Prashanth 2007).

Equally important, OPPNs can cause significant alteration in physical appearance secondary to proptosis, ptosis, and facial disfigurement, leading to social embarrassment and decreased self-esteem.

Analyzing the above selection criteria clearly indicates that some excipients used with an objective to modify the in-vivo dissolution and release profile of the drugs can cause significant alteration in its pharmacokinetic profile, resulting in alteration in its pharmacodynamic activity.

Nevertheless, it is well known that LS in adult women may cause significant alteration in vulvar architecture.

In only one study did irrigation with povidone-iodine solutions for deep sternal wound infection not cause significant alteration in thyroid function in children [ 86].

Among our 54 addition alleles, we identified at least four cases in which the new amino acid sequence can be predicted to cause significant alteration and/or expansion of a protein domain structure.

Homocystine treatment did not cause significant alterations in CBS levels (P=0.992).

Numerical results show that the inclusions near contact surface could cause significant alterations in the contact pressure distribution.

A similarly effective drug, entacapone, has not been shown to cause significant alterations of liver function.

These changes cause significant alterations in open reading frames of genes in surface structure biosynthesis loci and in genes with only putative functions.

Mutation of csrR or csrS can cause significant alterations in virulence in mouse models of infection,either increasing lethality or the severity of localized soft tissue lesions [5], [6].