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Peritonitis is a common cause of technique failure in peritoneal dialysis (PD).
Peritonitis is the leading cause of technique failure among long-term peritoneal dialysis (PD) patients.
During follow-up, 78 patients switched to HD. Peritonitis was the main cause of technique failure in both groups, followed by inadequate dialysis.
CPD-associated peritonitis is the most common infection in CPD patients and has been noted to be not only a major cause of morbidity and mortality but also the leading cause of technique failure of patients maintained on CPD [ 4].
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The causes of technique failure included fluid overload (n = 4), peritonitis (n = 1) and death (peritonitis n = 1, acute myocardial infarction n = 1).
The causes of technique failure and death were not reported in the Canadian study, so it is conceivable that these adverse clinical outcomes could be related to factors other than peritonitis.
The distribution of different causes of technique failure was similar between the two groups (Table 4; unadjusted data).> The technique survival rates at 1, 2, 3 and 5 years were 96.5%, 91.4%, 85.9% and 73.3%, respectively, for patients with NCMS, and 95.8%, 92.0%, 87.0% and 81.5%, respectively, for patients with UEMI (P = 0.245).
Despite substantial advances in peritoneal dialysis (PD) as a renal replacement modality, PD-related infection remains an important cause of morbidity, technique failure, and mortality.
This study confirms that Pseudomonas ESI is an important cause of PD technique failure.
Exit-site infection and peritonitis are of major concern and can be a cause of early technique failure.
They found neither a higher incidence of enteric peritonitis within the PKD cohort, nor any association between PKD as cause of PD technique failure.
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